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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be5613d7ef25724e36ee23ab25eac39e05a18b151ad04e256bb80b48cae2777f' 
  AND token = 'DHWN6g4fYixuZ//ryVbg0TW1BMpa4urX6TkzcyURhvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}