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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab468cb70a7df1ddcd34cf763197b186f20867ed7eb7203d40b597f65083a60d' 
  AND token = 'fuAC3nKms3WtOfFvU+4QkU2k43h1XM1nOseevsdwUz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}