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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e2224b9c6babb8adbe498a48ddd14bc4e08a21b20861d9a679cb0700e16c833' 
  AND token = '489trkvgjpFyVpKTjq8gPjLBdJZFLu4fMAoo+13PHlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}