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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ace7fd5d4e120f6fd47668ad1e68ee4e8eebecc75657de99f63f63d6dfd02380' 
  AND token = 'ipC0yKYM3YpUGPBppEw+fNLBDGxk5yKlHgkw28Jtf38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}