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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e4beae85c1f0b3c1939dad09409d09f70b7f027b2e36bbd74127a28a954eba' 
  AND token = 'ZjA7KwD0M41ig8Nk+ca4OM4lyFuqbnLpurNis3bPsPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}