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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd80997e07aa22a6522e8911673b8b63c9874b064cdf0720c01dce6638bb51f60' 
  AND token = 'ZYe1H6E6puhYT24IyECh8oegRvO95DgzUU6mBp0eD2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}