SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e592ff09eab380fb8379398f6a269820c2cca3410a5b668ab548b8f5e16d4d65' 
  AND token = 'SJ0CLDl+o1j72XBUw+o5ky77NiWS8MOBMDO7xHEtUYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}