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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fd81765e1fcf8ff5d2404b9312a3b028da6e410a4564144c843a322d2163e43' 
  AND token = 'R3m7RexhwyifVipOtnN/NyiU6lFDWaYhNY1bj57+hWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}