SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c00b57a5ac58a8a5dabbf33bafd6c95ec0d9e4c3f5ccc78de14d56774832205' 
  AND token = '5cjIVWWzjgHi1AP/ggtYH7C3cnewaIk/I58FLSa6CkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}