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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecf19b59bdbd61dc606dc98d76906f38f2dd6e35a51ba350be61162760e61fd8' 
  AND token = 'sGMUFC7A/EcuveR1qdvLSWWl9O1OwKgOU/5lk0I7T4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}