SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33328e88426c9f46d3642ac557bfcfa26f8bc03cc023d9a83ab259b6eab7aca8' 
  AND token = 'z5s4OPZsBGAt6pl2M8Gb5q721VgM/ihjumdW6JCoxLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}