SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33f361fc8e23274c2838b3af29763e2ebf2a872597f34bec0b311dd7912e5c11' 
  AND token = 'z3xGlcz7Aqn805sUZiKwv0UWtdAukyLfp1EIYm4FkCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}