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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49fb80304cef4c56570ebcd4eb887c3739f330f1a53afc378ff0111daf2b8f0' 
  AND token = 'V8UgUia1I5awmZO/NI6LW8nDZKN1voEC9vZ3PeIixZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}