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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea00c6530fa8e5a2a04a0cc0cce8dc2156cd3ba881c9af0d3c5686e74d53f7a' 
  AND token = '6GFF3ssL0YT0SX3PHOLEq/jDZLXL4RiHmuOTOd0rGGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}