SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '855545d1a6f715387e94418d47e9a475b902d1058a24b5968711be98d58de1c5' 
  AND token = 'xkWEkmMSq6MXUJ1x0VnxP2loAfJOARM6snJcVcKDEKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}