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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41443cd6e0d18509a69a4a7a8663c5ea97cd70e42d8b99b79f212fce7a4f2f15' 
  AND token = '4kSeakthTbY3pk1wPSO4+FsU6KQ6IocXCyNDXjD8mf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}