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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a0846f50e4da33b9bdf3993dc3e64f5ef90090e88c42a9a42b8bd333d316a2' 
  AND token = 'QEhmzFOpKrn3Hre9bXeHcCmYxjihgcCM16YWaxpdYIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}