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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '822fd839d2d75fcb2adc29c0132f821ce0504f5451098594ca03f95c70f84137' 
  AND token = 'e3k1pmsPQBQuh13NQ+D1aXLCrR7s/hBA409W/YzjL68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}