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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cbeb6cf9ec837dea0f65e5f6628f1ef99354d21d2ee21ccee754bebd77f1cb6' 
  AND token = 'quBJoMErvCbUZVIF8z+7n1IYDnO8K5KgUrSl8i0ynUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}