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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e87c6ae125d682400b7ecb6e6603438b90a327c1124e86ed73abad060e568032' 
  AND token = 'ryGZRm3ptaG+4QuufdOasvQ/a3B22AJ0AnrSfX/IU4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}