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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '345f6d210e2d65496501c8d71c6ffc3aa27a1f73319aa365c7cdadce8ae092ec' 
  AND token = 'vnYX8mLtO2zYXSBZq7UYMrYJAzd3uxPfQvHueMGutKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}