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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b20d4234d501913c21bf0bdda3c4f109f8a6d5a703fd4158cf8dc8721f2e4775' 
  AND token = 'zvEEiYywpW31EFuQUOFtrAo1BneUZFp8PSFoTLYUP5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}