SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c609289da1f0ecb1559765d156368f69748f57106e55dcb26e90386cfa1ef804' 
  AND token = 'uPJ1OGLI0I/8yFsuD+f0I4Lf4KNvUvxAeDUHJS8CGrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}