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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57cdf661e7a0a7f50cb4c5ab1de88593ed09d1ac82c9ae05f4a04b83a7cce980' 
  AND token = 'pjCNje8/yro3H9+DviRH64dqU6bnJlTu76zDG9Nf4qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}