SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c432ed7b4449964b52482617568591479ce9b40219124a4760b0195d796dabf' 
  AND token = '72s0HVkbepSV/xwnkJ0r5DpjjhrjnpnI3qv+lQwJ9YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}