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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2709c7534bf1e6b0f0909177e482a77d1511551a6082c02f26872449d8cf8847' 
  AND token = 'r3Y8FqOF4OHXrHvkQaUt7G5LlEZqwhOQsMshNMouKRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}