SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8adcf851019b7fd2408bc10af4ae9001c9ce235a528d85d841997a12c5973ab' 
  AND token = 'qDNiPgebhKYX72DIoVhmfH3MNjbXOxXt8tb3qj2RfQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}