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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3214995e760c628b7cad99d7d2fda9d8b3893a85655bdb2f803694c7d0d71c' 
  AND token = 'nO0xkg/Wd1AVM1SMELkiGuM2uc0cA6+Mb2c29wfT1Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}