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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2ee5a9d09ca255162c6e13981cbf609933fc6fb7b9caa318073cd06e887f0f9' 
  AND token = 'YOoY7A0ngW9Z2B43GFUbcEEZ61F6q047aypsCT5vw4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}