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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aedab7110562b0406aba09b992388bfacf08918edfe76ec0b16299c65c381bb5' 
  AND token = 'GIpL4ZWvAQGp3jV6jZC18zetZItBNG0pQCHJrFnQpPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}