SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '207b4c4e557c98e36af30b4c0fe323b8423003106bdb87a2423bd3422f392309' 
  AND token = 'BP2AEFmH+OuYDGBQvtKfPgYte7GiH1rWSSHByOS0EBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}