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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f2a64016ff3c725e00ebb114ecf265284dbe8271ad2ed299da303b71eea7d9a' 
  AND token = '00BVpVQJhA1xKwhxfz8FYzfwGfak3wWcfr1YDCljCbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}