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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce69f542159968f4b602d8fe5c57533b24580c51c1dde4a26d7b192dd3b7587b' 
  AND token = 'CQvXvaaU+9gh4b1h3lq4TxZnFeHky4C8YqiOEEBeDmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}