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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1043e2ae6401f102c0bc880255b1dbced3e5ad51922fc94ba8964d67a46540d3' 
  AND token = '4+wrsEnK4uGvJYILerK392aTMXyqVEcWva0l4Mr866M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}