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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '563b1b31c034af60c57a6425050cc86faae38dd0228164b4dca70e1086e66b77' 
  AND token = '2eJkEiay0C4UQ1xDNCMpGd09QO6snDUhAYfaYJjJYJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}