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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26d452fcb61cdec74cb1529c2ecd7e16ce342addb1b508d289c333552e19832a' 
  AND token = 'R6VwWmWNT9qQtW9PXgA2QAkehemwcAj9fafMc+6ydJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}