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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '475ea11d34ca8e5387d305d53a0036043243b374ed63a22b6f97ffd3b8a20725' 
  AND token = 'YwHPUKdfNMh3nvND/4X2fjpJfCPrbmavC+JIwxgtEm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}