SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8224d0e69b02e540eb32a3a3fe66fe1c9fae86fdab85b816a8f67dd157f73520' 
  AND token = 'SQ/W0f7/SnmG2JEmZ9Am40vQ68AojXetgI8aMGD3t6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}