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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd5605d0503d4fe24d5f9698f517e91a63d3d6129f4ce4cc39ba1b36871bd15b' 
  AND token = 'IHE8KdLOG1GtWXplCeSH6kQ0/fikoxDQCc61dxnFkfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}