SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c45a0a83ca083cf80ef1d0f2b6693d581660496d25f51b30b918a56e9fd7ed72' 
  AND token = 'ZKFPK7LYXjAwolAOgSV4sq6DuTet2EvgVPpNnHIU7KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}