SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab04faf249e0ad74d29425794b10f3d1a75247b29c6e6c42e43b2b2a18cca897' 
  AND token = 'D1O6KYYoZlwhv+TqSChaHInULrLU2UsAumnCUga+3+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}