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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91fdcb55006a2ab1a023fc05f330d60a872e294a1dc0d79fb65c13820db47654' 
  AND token = 'lwmTa5Mi0SqM8PLudshwztkOFy97C8gc8M8E/m3HTCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}