SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eead7100de23695f7db594d37fe28ca53b1d835e5c3ef3c3d3c0c2038548af61' 
  AND token = 'ZSbhHaJG2PBclqr1zOxUmYx8tDJCQddGjbg4/AZEnD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}