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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4c9d27b25012d78f98e025f75632dc67d3179d45ea89479592d019c71c6dd77' 
  AND token = 'qs/FJQS+UeVzQPD/QzbyzW3Uq96BNScLGODBA8npUqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}