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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e8828726caeffc959529e94a379e55fb43b20311d15d0e990e123db6305c9ec' 
  AND token = 'tW4eT4KN0Dpyr75sz31mF9JERIeeOGRtT+A1PCzwazs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}