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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53417d2cfda1ac6efe97fc7f8e8ef5e5e801c24e8cf942df2bb5260ff3765da6' 
  AND token = 'Yb9y8LheLKT/3jtu9/RprRF5BF6fzQfYgus+r6+B7uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}