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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '183249040be15f802b40dd965c3e67a9a949da8c460c77f6ac6a0c4e7f421891' 
  AND token = '+RpVpjkxM+W02c+bNp7pRARnFfIa8f+Tff+gISWTgSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}