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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab9d9874ddd017b21db8000faf685b30526cbb6578e771ceffae5e2cc80c45d' 
  AND token = 'nEkrLzPY0Y0C6NGHKIKv22qUUU2tUrEJv4+yGJUwfOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}