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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c0f9f027e4ffb287ed7ee3d8a7f43b8988a9812ef18f8929e7406d8f355ef8' 
  AND token = '64MuBsTWbV4zdrAi+ht7XYPiz2tJhLBrB8xM0ztKz2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}