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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7ce63b47acbe2c375f825cc0ac128b737a6e4d8d8a0898a55014ab6bd1dc929' 
  AND token = 'bI1B4dvpJezyQoWct8jVFRIdkPBgWjkZC70SNg+IjDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}